WebFeb 5, 2024 · CTCF physically interacts with MRE11 and CtIP and promotes CtIP recruitment to sites of DNA damage. Subsequently, CTCF facilitates DNA end resection to allow HR, in conjunction with MRE11-CtIP ... WebCTCF (CCCTC-binding factor) is a multiple zinc finger protein that exerts diversified functions under different genomic contexts. CTCF was first isolated and cloned on the …
The structural basis for cohesin–CTCF-anchored loops
WebJan 14, 2024 · Peripheral blood mononuclear cells (PBMCs) belong to the innate and adaptive immune system and are highly sensitive and responsive to changes in their systemic environment. In this study, we focused on the time course of transcriptional changes in freshly isolated human PBMCs 4, 8, 24 and 48 h after onset of stimulation … WebMar 9, 2024 · HB-EGF promotes enteric neural stem cell proliferation and migration in a mouse model. mice in which DTR is expressed on conventional Dendritic cells display … bip stand 2022
IJMS Free Full-Text Time-Resolved Gene Expression Analysis …
WebMar 11, 2014 · CTCF is conserved in most bilaterian phyla but is absent in yeast, Caenorhabditis elegans and plants 5.It contains a highly conserved DNA-binding domain with 11 zinc-fingers 6; it is present at ... WebSep 15, 2024 · The three-dimensional genome organization is critical for gene regulation and can malfunction in diseases like cancer. As a key regulator of genome organization, … Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. HB-EGF-like growth factor is synthesized as a membrane-anchored mitogenic and chemotactic glycoprotein. An epidermal growth factor produced by … See more Heparin-binding EGF-like growth factor has been shown to interact with NRD1, Zinc finger and BTB domain-containing protein 16 and BAG1. HB-EGF biological activities with these genes influence cell … See more Recent studies indicate significant HB-EGF gene expression elevation in a number of human cancers as well as cancer-derived cell lines. Evidence indicates that HB … See more HB-EGF is the predominant growth factor in the epithelialization required for cutaneous wound healing. The mitogenic and migratory … See more • Higashiyama S, Lau K, Besner GE, et al. (1992). "Structure of heparin-binding EGF-like growth factor. Multiple forms, primary structure, and glycosylation of the mature protein" See more HB-EGF binding and activation of EGF receptors plays a critical role during cardiac valve tissue development and the maintenance of normal heart function in adults. During valve tissue development the interaction of HB-EGF with EGF receptors and … See more HB-EGF is recognized as an important component for the modulation of cell activity in various biological interactions. Found widely distributed in cerebral neurons and … See more • heparin-binding EGF-like growth factor at the U.S. National Library of Medicine Medical Subject Headings (MeSH) See more bip stbg20cy