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Frontiers Mitochondrial Heme Synthesis Enzymes as Therapeutic …
WebIt was recently found to be the receptor for heme and its plasma-binding protein hemopexin (Hx) and is integral to systemic heme clearance. Little is known about systemic concentrations of Hx during pregnancy and whether maternal Hx and placental LRP1 contributes to fetal iron (Fe) homeostasis during pregnancy. Webe proin ammatory vasculotoxic e ects of intravascular hemolysis are modulated by plasma hemoglobin and heme clearance via the haptoglobin/CD system and the hemopexin/CD system, respectively, and detoxi cation through the heme oxygenase/ferritin system. However, sudden or excessive hem olysis can overwhelm these protective systems … mcgraw hill connect chapter 7 answers
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